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To solve problems with impaired potency, sexual desire, or early ejaculation, there are a huge number of drugs. Viagra is one of the most effective means of strengthening sexual function. The composition of this dietary supplement includes only plant substances, so the risk of negative reactions or overdose is minimal. The drug is also recommended for women to exacerbate sexual sensations and increase libido.

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Pharmacological properties

The main active ingredient of the tablets affects the erection in a man during the onset of excitement by increasing blood flow to the cavernous bodies of the penis. Sildenafil inhibits the phosphodiesterase type 5 enzyme. This leads to an increase in the content of cyclic AMP, which causes relaxation of the smooth muscles of the walls of the blood capillaries and cavernous bodies of the penis, and also increases their filling with blood, causing an erection.
Also, when excited, nitric oxide is produced, which activates an increase in the content of cyclic adenosine monophosphate. The active ingredient in Viagra is believed to increase the effects of nitric oxide. The main condition for obtaining a positive effect from the use of this medication is the presence of sexual stimulation of a man and his arousal.
After taking the tablet, sildenafil is quickly absorbed from the lumen of the small intestine into the blood. Its maximum pharmacological content is reached within thirty minutes after the use of the drug, the maximum concentration is after one hour.
When taking the drug orally after a meal, the rate of absorption is slightly lower than on an empty stomach. The main component is evenly distributed throughout all tissues. Its metabolism is carried out in the liver cells with the appearance of intermediate decay products that are excreted from the body with feces. The half-life is four hours.

Indications

The main indication for the use of the drug is the correction of sexual erectile dysfunction in a man for sexual intercourse. The main condition for achieving the result is the presence of sexual arousal in a man.

What contraindications does the drug have?

The use of Viagra is prohibited in certain pathologies and conditions of the body, which include:

  • Individual intolerance or hypersensitivity to sildenafil.

  • Simultaneous administration of tablets and other drugs containing nitric oxide, which can provoke a hypotensive effect and lead to an increased decrease in total blood pressure.

  • Try to take the pills regularly and at the same time. The most efficient strategy is to maintain a constant level of its active ingredient in the human body to prevent the replication of the viruses.

  • Severe cardiovascular disease.

  • Ischemic heart disease.

  • Stable or unstable angina.

  • Acute or chronic heart disease.

  • Myocardial infarction.

  • Arterial hypotension.

  • Diseases of the kidneys and liver.

  • Retinal degeneration.

  • Apoplexy- an acute violation of the blood circulation of the brain, leading to damage and death of nerve cells.

The presence of contraindications should be determined even before the use of the drug.

How to use the drug correctly?

Tablets are taken orally, regardless of the use of food (bioavailability and the rate of absorption of the active component of the drug from the intestine are greater on an empty stomach).
How to take Viagra for men for the first time? The drug should be used immediately after removal from the blister since prolonged exposure to air can reduce the content and activity of sildenafil.
And also, during use, the tablet should be held in the mouth for a short time until it softens and then swallowed, for better movement of the tablet through the esophagus, it can be washed down with water.
According to reviews, it is correct to take Viagra one hour before intimacy (to achieve the best effect). In liver diseases, the dosage of the substance taken is reduced to twenty-five milligrams.
The recommended dosage is fifty milligrams, if necessary, it can be increased to one hundred milligrams. The maximum daily concentration is 100 mg per application.

Adverse reactions

After taking Viagra, negative effects may occur, which depend on the dosage. Such detrimental reactions can manifest themselves from various systems, they include:

  • Abdominal pain.

  • Unstable chair.

  • Vertigo.

  • Nausea.

  • Insomnia.

  • Increased muscle tone.

  • Nasal congestion.

  • Vomit.

  • Laryngitis.

  • Pharyngitis.

  • Urethritis.

  • Cystitis.

  • Conjunctivitis.

  • Myalgia.

  • Priapism.

  • Urticaria.

If adverse reactions occur, the use of the drug should be discontinued, and consult a doctor.
Viagra should be used with caution in men who have anatomical disorders of the penis, which can be pronounced during its erection.
You can not use pills for people with a predisposition to a longer erection, as well as for sickle cell anemia, leukemia, multiple myeloma.
To get a good effect after using Viagra, sexual stimulation is needed.
Do not use the drug during work that requires increased attention or speed of psychomotor reactions.